NIAID Confirms IPA’s PolyTope TATX-03 Neutralizing Activity Against the Currently Spreading SARS-CoV-2 Variant BA.2.75
VICTORIA, BRITISH COLUMBIA (CANADA), September 14, 2022 – IPA (IMMUNOPRECISE ANTIBODIES LTD.) (the “Company” or “IPA”) (NASDAQ: IPA) (TSXV: IPA), announced today that its subsidiary, Talem Therapeutics LLC (“Talem”), has shared positive results of a new study conducted by the National Institute of Allergy and Infectious Disease (NIAID), part of the National Institutes of Health (NIH), that has shown the continued resilience of PolyTope® TATX-03 in broadly neutralizing SARS-Co-V-2 variants, including two Omicron sublineages that had not been previously tested.
This NIAID-conducted pseudovirus-based study has reconfirmed the neutralizing activity of TATX-03 against the European variant (D614G mutant) of the parental virus and several previously tested variants, including Delta (B.1.617.2), and Omicron sublineages (BA.2, BA.4/5). Importantly, TATX-03 has now demonstrated its neutralizing activity against the currently spreading BA.2.75 variant. Maintained neutralizing potency was also confirmed for the Omicron sublineage BA.2.12.1, SARS-Co-V-2 variant that had not yet been screened in virus neutralization studies.
IPA’s Chief Scientific Officer (CSO), Dr. Ilse Roodink, stated: “We appreciate that our interactions with the FDA resulted in this collaboration with the NIAID. This division of the NIH is continuously screening clinical-stage antibody therapeutics for neutralizing potency towards emerging variants. We highly value this independent validation of the resilience of our PolyTope® TATX-03 product, further strengthening our position as we progress into clinical trials in humans.”
ImmunoPrecise Antibodies Ltd.
ImmunoPrecise Antibodies Ltd. is a biotherapeutic research and technology company that leverages systems biology, multi-omics modelling and complex artificial intelligence systems to support its proprietary technologies in bioplatform-based antibody discovery. Services include highly specialized, full-continuum therapeutic biologics discovery, development, and out-licensing to support its business partners in their quest to discover and develop novel biologics against the most challenging targets. For further information, visit www.ipatherapeutics.com.
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Forward Looking Information
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Forward-looking information involves known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements stated herein to be materially different from any future results, performance or achievements expressed or implied by the forward-looking information. Actual results could differ materially from those currently anticipated due to a number of factors and risks, including, without limitation, the Company may not be successful in timely submission of an application for regulatory approval, developing its PolyTope® TATX-03 through the successful and timely completion of clinical trials, or may not receive all regulatory approvals to commence and then continue clinical trials of PolyTope® TATX-03, as well as those risks discussed in the Company’s Annual Information Form dated July 29, 2022 (which may be viewed on the Company’s profile at www.sedar.com) and the Company’s Form 40-F, dated July 29, 2022 (which may be viewed on the Company’s profile at www.sec.gov). Should one or more of these risks or uncertainties materialize, or should assumptions underlying the forward-looking statements prove incorrect, actual results, performance, or achievements may vary materially from those expressed or implied by the forward-looking statements contained in this news release. Accordingly, readers should not place undue reliance on forward-looking information contained in this news release.
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